Gov. Jay Nixon announced the five-year grant Tuesday for farmers in the North Fork Salt Watershed, which drains into Mark Twain Lake.
The grant will provide financial and technical assistance to farmers in Adair, Knox, Macon and Shelby counties.
The project is part of the Mississippi River Basin Initiative, a 12-state effort funded by the U.S. Department of Agriculture. Part of the goal is to limit agricultural runoff that makes its way into the Mississippi, requiring extra treatment of drinking water.
Missouri is expected to receive more than $28 million for 12 projects over five years.